Careers

  The Clinical Project Manager (CPM) will coordinate with the Clinical Research Organizations (CRO) vendor(s) that Tavotek commissioned to conduct clinical trials on various early phase clinical assets in immunology and oncology. Initial responsibilities include coordinating with CROs in the preparation and submission of documents necessary for clinical studies, subsequent preparation of case report forms, monitoring and managing data, communicating with KOLs, PIs or other relevant stakeholders to ensure smooth execution of company sponsored clinical studies. The CRM will report directly to the Vice President of Clinical Operations or Chief Medical Officer. Job location will be based in Spring House, PA (Greater Philadelphia). 

Desired Skills and Requirements:

• Bachelor’s Degree in a science major or equivalent education. Priority will be given to candidates with training in Project Management and clinical trial execution.
• 1–5-year prior work experience as a Clinical Research Associate or Clinical Project Manager in a CRO or a biopharmaceutical company.
• Prior experience in running Phase 1 healthy volunteer studies is desired but not required.
• Multilingual (English & Mandarin) especially with ability to communicate with clinical CROs and clinical study sites in Asia is desired but not required.
• Strong oral and written communication skills; strong organizational skills and work ethics; ability to work independently and in a collaborative setting.
• Must be willing to travel up to 10%. This includes occasional clinical site visit to coordinate with PIs and CRO representatives. 

 The Associate Director/Director of Nonclinical Development will serve in a highly visible role in advancing Tavotek biologic drug development portfolio from lead to IND submission. He/she will partner with internal teams, CDMO/toxicology CRO and external consultants to develop and manage timelines, development plans, budgets as well as milestones.

Desired Skills and Requirements:

• An advance degree in relevant scientific discipline with at least 8 years of related experience
• Ability to understand scientific data
• Understanding of biologics in CMC development and manufacturing
• Knowledge in toxicology relevant to regulatory submissions
• Hands on experience in working with and/or managing both CDMO and toxicology CRO for biologic drug development 
• Experience in collaborating with external consultants and internal teams
• Review technical reports and summary documents for regulatory submissions
• Ability to work independently and prioritize assignments to meet aggressive project timelines
• Independent self-starter who is comfortable working in a cross-functional team-based drug discovery/development environment
• Highly motivated team player who is willing to contribute to a fast-growing biotech organization
• Project management skill set preferred

 Desired Skills and Requirements:

• Ph.D. degree in the biological sciences or related education (immunology, cancer biology, molecular biology)
• Minimal 5 years of relevant research experience, in academic, pharmaceutical or biotechnology settings 
• In depth knowledge in both immunology and cancer biology spaces, including T cell/NK cell biology, MHC-TCR interactions, and T cell/NK cell activation in tumor microenvironment  
• Expert in the design and execution of PBMC-based in vitro and ex vivo potency assays, particularly antigen-specific T cell activation and proliferation assays and tumor cell cytotoxicity assays 
• Creative thinking skills and strong research ability in the design, evaluation and optimization biologics drug molecules 
• Ability to handle multiple programs in a collaborative team setting 
• Ability to acquire additional competencies and skill sets as required by the changing needs of the organization

 Desired Skills and Requirements:

• B.A. / B.S. / M.S. or equivalent degree in the biological sciences or related education (immunology, molecular biology, biochemistry, protein chemistry) 
• 2-5 years of relevant laboratory experience, in academic, pharmaceutical or biotechnology settings
• Experience in protein expression in bacteria and mammalian cell expression system
• Experience in purification and analysis of biologics drug molecules 
• Experience in HPLC-based bioanalytical methods for biologics is a plus  
• Ability to handle multiple programs in a collaborative team setting 
• Ability to acquire additional competencies and skill sets as required by the changing needs of the organization

 Desired Skills and Requirements: 

• B.A. / B.S. / M.S. or equivalent degree in the biological sciences or related education (molecular biology, biochemistry, cell biology, immunology) ·
• 2-5 years of relevant laboratory experience, in academic, pharmaceutical or biotechnology settings
• Experience in development of biological assays, including ELISA, ow cytometry and cell based potency assays 
• Experience in performing in vitro, and ex vivo assays for the study of biologics drug molecules
• Ability to handle multiple programs in a collaborative team setting 
• Ability to acquire additional competencies and skill sets as required by the changing needs of the organization