Careers

 The Associate Director/Director of Nonclinical Development will serve in a highly visible role in advancing Tavotek biologic drug development portfolio from lead to IND submission. He/she will partner with internal teams, CDMO/toxicology CRO and external consultants to develop and manage timelines, development plans, budgets as well as milestones.

Desired Skills and Requirements:

• An advance degree in relevant scientific discipline with at least 8 years of related experience
• Ability to understand scientific data
• Understanding of biologics in CMC development and manufacturing
• Knowledge in toxicology relevant to regulatory submissions
• Hands on experience in working with and/or managing both CDMO and toxicology CRO for biologic drug development 
• Experience in collaborating with external consultants and internal teams
• Review technical reports and summary documents for regulatory submissions
• Ability to work independently and prioritize assignments to meet aggressive project timelines
• Independent self-starter who is comfortable working in a cross-functional team-based drug discovery/development environment
• Highly motivated team player who is willing to contribute to a fast-growing biotech organization
• Project management skill set preferred

 Desired Skills and Requirements:

• Ph.D. degree in the biological sciences or related education (immunology, cancer biology, molecular biology)
• Minimal 5 years of relevant research experience, in academic, pharmaceutical or biotechnology settings 
• In depth knowledge in both immunology and cancer biology spaces, including T cell/NK cell biology, MHC-TCR interactions, and T cell/NK cell activation in tumor microenvironment  
• Expert in the design and execution of PBMC-based in vitro and ex vivo potency assays, particularly antigen-specific T cell activation and proliferation assays and tumor cell cytotoxicity assays 
• Creative thinking skills and strong research ability in the design, evaluation and optimization biologics drug molecules 
• Ability to handle multiple programs in a collaborative team setting 
• Ability to acquire additional competencies and skill sets as required by the changing needs of the organization

 Desired Skills and Requirements:

• B.A. / B.S. / M.S. or equivalent degree in the biological sciences or related education (immunology, molecular biology, biochemistry, protein chemistry) 
• 2-5 years of relevant laboratory experience, in academic, pharmaceutical or biotechnology settings
• Experience in protein expression in bacteria and mammalian cell expression system
• Experience in purification and analysis of biologics drug molecules 
• Experience in HPLC-based bioanalytical methods for biologics is a plus  
• Ability to handle multiple programs in a collaborative team setting 
• Ability to acquire additional competencies and skill sets as required by the changing needs of the organization

 Desired Skills and Requirements: 

• B.A. / B.S. / M.S. or equivalent degree in the biological sciences or related education (molecular biology, biochemistry, cell biology, immunology) ·
• 2-5 years of relevant laboratory experience, in academic, pharmaceutical or biotechnology settings
• Experience in development of biological assays, including ELISA, ow cytometry and cell based potency assays 
• Experience in performing in vitro, and ex vivo assays for the study of biologics drug molecules
• Ability to handle multiple programs in a collaborative team setting 
• Ability to acquire additional competencies and skill sets as required by the changing needs of the organization